| Date | Location | Result | |
| Nov 28, 2020 | Hershey, Pa. | Southern Columbia 42, Wilmington 14 | Box score |
| Nov 20, 2020 | Beaver Falls, Pa. | Wilmington 20, Beaver Falls 18 | Box score |
| Nov 20, 2020 | Transfer, Pa. | Jeannette 48, Reynolds 12 | Box score |
| Nov 13, 2020 | New Wilmington, Pa. | Wilmington 56, Chestnut Ridge 29 | Box score |
| Nov 14, 2020 | Brockway, Pa. | Reynolds 19, Redbank Valley 14 | Box score |
| Nov 13, 2020 | Windber, Pa. | Bedford 34, Hickory 17 | Box score |
| Nov 06, 2020 | WARREN, Pa. | Warren 34, Sharpsville 28 | Box score |
| Nov. 6, 2020 | New Wilmington, Pa. | Wilmington 42, Karns City 14 | Box score |
| Nov 07, 2020 | Hermitage, Pa. | Hickory 42, Grove City 29 | Box score |
| Nov 06, 2020 | Russell, Pa. | Reynolds 27, Eisenhower 0 | Box score |
| Oct 31 2020 | Franklin, Pa. | Lakeview 46, Franklin 25 | Box score |
| Oct 30, 2020 | Mercer, Pa. | Mercer 32, Cochranton 8 | Box score |
| Oct 30 2020 | Transfer, Pa. | Reynolds 40, Cambridge Springs 0 | Box score |
| Oct 30 2020 | Greenville, Pa. | Sharpsville 21, Greenville 0 | Box score |
| Oct 31 2020 | Hermitage, Pa. | Hickory 51, Slippery Rock 0 | Box score |
| Oct 31 2020 | Lander, Pa. | Eisenhower 22, West Middlesex 21 | Box score |
| Oct 31, 2020 | New Wilmington, Pa. | Wilmington 19, Farrell 14 | Box score |
| Oct 30, 2020 | Waterford, Pa. | Grove City 30, Fort LeBoeuf 0 | Box score |
| Oct 23, 2020 | Greenville, Pa. | Sharon 42, Greenville 15 | Box score |
| Oct 23, 2020 | Butler, Pa. | Butler 28, Slippery Rock 3 | Box score |
| Oct 24, 2020 | Hermitage, Pa. | Cambridge Springs 45, Kennedy Catholic 8 | Box score |
| Oct 24, 2020 | Albion, Pa. | Farrell 30, Northwestern 10 | Box score |
| Oct 23, 2020 | Stoneboro, Pa. | Lakeview 47, Mercer 7 | Box score |
| Oct 16, 2020 | Cambridge Springs Pa | Cambridge Springs 29, Lakeview 18 | Box score |
| Oct 17, 2020 | Hermitage, Pa. | Reynolds 34, Kennedy Catholic 18 | Box score |
| Oct 15, 2020 | Farrell, Pa. | Farrell 30, Greenville 8 | Box score |
| Oct 15, 2020 | Sharpsville, Pa. | Wilmington 57, Sharpsville 14 | Box score |
| Oct 15, 2020 | Grove City, Pa. | Grove City 14, Sharon 13 | Box score |
| Oct 17, 2020 | Hermitage, Pa. | Hickory 28, Slippery Rock 7 | Box score |
| Oct 16, 2020 | Mercer, Pa. | West Middlesex 31, Mercer 0 | Box score |
| Oct 10, 2020 | Albion, Pa. | Northwestern 31, Lakeview 14 | Box score |
| Oct 9, 2020 | Mercer, Pa. | Reynolds 41, Mercer 0 | Box score |
| Oct 09, 2020 | West Middlesex, Pa. | West Middlesex 26, Kennedy Catholic 0 | Box score |
| Oct 9, 2020 | Hermitage, Pa. | Hickory 41, Sharon 28 | Box score |
| Oct 09, 2020 | Sharpsville, Pa. | Sharpsville 24, Greenville 14 | Box score |
| Oct 10, 2020 | New Wilmington, Pa. | Wilmington 21, Farrell 20 | Box score |
| Oct 09, 2020 | Slippery Rock, Pa. | Slippery Rock 17, Grove City 14 | Box score |
| Oct 02, 2020 | Stoneboro, Pa. | Lakeview 22, Saegertown 12 | Box score |
| Oct 03, 2020 | Hermitage, Pa. | Mercer 26, Kennedy Catholic 0 | Box score |
| Oct 02, 2020 | Farrell, Pa. | Farrell 51, Sharpsville 7 | Box score |
| Oct 02, 2020 | Greenville, Pa. | Wilmington 48, Greenville 6 | Box score |
| Oct 02, 2020 | Sharon, Pa. | Sharon 31, Slippery Rock 20 | Box score |
| Oct 02, 2020 | Grove City, Pa. | Hickory 28, Grove City 7 | Box score |
| Oct. 2, 2020 | Transfer, Pa. | Reynolds 36, West Middlesex 14 | Box score |
| Sep 25, 2020 | Guys Mills, Pa. | Maplewood 30, Lakeview 22 | Box score |
| Sep 25, 2020 | Transfer, Pa. | Reynolds 75, Kennedy Catholic 14 | Box score |
| Sep 25, 2020 | Greenville, Pa. | Farrell 47, Greenville 7 | Box score |
| Sep 25, 2020 | New Wilmington, Pa. | Wilmington 42, Sharpsville 0 | Box score |
| Sep 26, 2020 | Sharon, Pa. | Grove City 42, Sharon 17 | Box score |
| Sep 26, 2020 | Slippery Rock, Pa. | Hickory 45, Slippery Rock 0 | Box score |
| Sep 25, 2020 | West Middlesex, Pa. | West Middlesex 35, Mercer 7 | Box score |
| Sep 18, 2020 | Stoneboro, Pa. | Lakeview 26, Cochranton 0 | Box score |
| Sep 18, 2020 | Transfer, Pa. | Reynolds 47, Mercer 0 | Box score |
| Sep 18, 2020 | Greenville, Pa. | Sharpsville 14, Greenville 12 | Box score |
| Sep 18, 2020 | Farrell, Pa. | Wilmington 41, Farrell 20 | Box score |
| Sep 18, 2020 | Sharon, Pa. | Hickory 48, Sharon 16 | Box score |
| Sep 19, 2020 | Hermitage, Pa. | West Middlesex 10, Kennedy Catholic 0 | Box score |
| Sep 18, 2020 | Grove City, Pa. | Grove City 34, Slippery Rock 21 | Box score |
| Sep 12, 2020 | Stoneboro, Pa. | Cambridge Springs 41, Lakeview 13 | Box score |
| Sep 12, 2020 | Sharpsville, Pa. | Farrell 41, Sharpsville 0 | Box score |
| Sep 12, 2020 | Mercer, Pa. | Mercer 46, Kennedy Catholic 6 | Box score |
| Sep 11, 2020 | West Middlesex, Pa. | Reynolds 27, West Middlesex 20 | Box score |
| Sep 11, 2020 | Hermitage, Pa. | Hickory 41, Grove City 21 | Box score |
| Sep 12, 2020 | New Wilmington, Pa. | Wilmington 48, Greenville 0 | Box score |
| Sep 11, 2020 | Slippery Rock, Pa. | Slippery Rock 27, Sharon 7 | Box score |